From Lab Bench to Breakthrough: How a UT Mentor-Student Partnership Sparked a Rising East Tennessee Biotech Company

When Trey Fisher, PhD, walked into the vascular biology lab led by Deidra Mountain, PhD, at the University of Tennessee Health Science Center College of Medicine – Knoxville more than a decade ago, he was a graduate student looking for a scientific challenge. He found one, and something more: the beginnings of a partnership that would one […]
Orion Therapeutics awarded NSF Phase II STTR grant to advance lead asset for restenosis, powered by our GENESYS™ targeted delivery platform

We are excited to announce that Orion Therapeutics has been awarded an NSF Phase II STTR grant to advance our lead asset for restenosis, powered by our GENESYS™ targeted delivery platform. This funding will support studies that both move our asset toward IND-enabling development and further validate the GENESYS™ platform as a lipopeptide-enabled lipid nanoparticle […]
Chiesi Global Rare Diseases and BioLabs announce Orion Therapeutics, Inc. as the winner of the recent US Network Golden Ticket

🎉 We’re thrilled to share some exciting news! 🎉Chiesi Global Rare Diseases and BioLabs are proud to announce Orion Therapeutics, Inc. as the winner of the recent US Network Golden Ticket!A huge congratulations to the entire team at Orion Therapeutics, Inc on this incredible achievement — well deserved!
Volunteer 40 Under 40: Recognizing alumni under the age of 40 excelling personally and professionally since completing their degree at UT

Exciting News! Our CEO, Trey Fisher, PhD has been named a 2025 Volunteer 40 Under 40 Award recipient by the University of Tennessee, Knoxville!🎉 We’re grateful for Trey’s leadership and vision as Orion Therapeutics, Inc. advances LNP-RNA delivery and genetic medicine to tackle critical health challenges. His dedication to innovation and patient impact continues to […]
Why a semi-retired baby boomer chose a passion project over a life of leisure: ‘There’s just an adrenaline rush’

For nearly a decade, Michael McCaman had an idea for a company — he just needed the right opportunity. Two years ago, when he was 68, that opportunity arose: McCaman cofounded Orion Therapeutics, a small company developing new ways for RNA medicine to reach specific areas of the human body. McCaman is among the older […]